Some NPCs need to get to specific spots before the next dialogue/event/walk-to-point is triggered. Blocking their path in confined spaces might hinder the player from getting out of the NPC‘s way, thus preventing gameplay progress. This might also happen accidentally when moving NPCs are trying to get to a specific point in a confined space, thus preventing the player from exiting (and the NPC from getting to its target point). If that happens, reload the last autosave (usually when entering the scene, sometimes within scenes) and replay until you get past the block.
While being in the Doomsday club, Richard needs to interact with the barmaid. Sometimes it can occur that one of the flying drones blocks the hotspot for a short amount of time by flying right above Louisa. In that case, wait for a moment, walk around, and after a short amount of time, the drone should fly away.